| Tuesday, July 12th, 1966 | Activated CF Ramón Medina from the disabled list. | Wednesday, June 15th, 1966 | Promoted SP Mike Decker to Double A Frankfort. | Received MR Ken Thomas from Double A Frankfort. | Drafted C Felipe Hernández in the 1966 first-year player draft (Round 6, Pick 1, 94th overall pick). | Drafted SP Jimmy Cairns in the 1966 first-year player draft (Round 7, Pick 1, 112nd overall pick). | Drafted 2B Guan-cai Ru in the 1966 first-year player draft (Round 8, Pick 1, 130th overall pick). | Drafted MR Wilbert Cole in the 1966 first-year player draft (Round 9, Pick 1, 148th overall pick). | Drafted MR Jody Kuhn in the 1966 first-year player draft (Round 10, Pick 1, 166th overall pick). | Thursday, June 9th, 1966 | Placed LF Vicente Guerrero on the 15-day disabled list. | Wednesday, May 25th, 1966 | Placed SP Lynn Hopkins on the 15-day disabled list. | Monday, May 23rd, 1966 | Placed SP Sam Dixon on the 15-day disabled list. | Monday, April 18th, 1966 | Released 1B Bob Moss. | Thursday, November 18th, 1965 | Activated SP José Aguilar from the disabled list. | |
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