| Sunday, April 26th, 1981 | Placed SS Ronald McKinney on the South Texas League 15-day disabled list. | Tuesday, March 24th, 1981 | Placed SS Jason Thomas on the 9-day disabled list. | Wednesday, March 11th, 1981 | Activated RF Adrian Rollins from the 60-day disabled list. | 1B Michael Tucker was designated for assignment, placed on waivers and taken off the 40-man roster. | Thursday, December 4th, 1980 | MR Kumanosuke Ageda was designated for assignment, placed on waivers and taken off the 40-man roster. | Monday, December 1st, 1980 | MR Román Cruz was designated for assignment, placed on waivers and taken off the 40-man roster. | RF Claude Brown was placed on the 40-man roster. | RF Christian Neale was placed on the 40-man roster. | Saturday, November 29th, 1980 | Signed MR Felipe Ramírez to a minor league contract. | Friday, November 28th, 1980 | Placed 1B George Rogers on the Golden Horseshoe League 15-day disabled list. | Saturday, October 25th, 1980 | Signed hitting coach Álex Cruz to a 5-year, $37,600 per year contract. | |
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