| Monday, July 10th, 1961 | Placed SP Arturo Ramírez on the 15-day disabled list. | Thursday, June 15th, 1961 | Promoted MR Brian O'Day to Double A Laredo. | Promoted CF Juan Mejía to Double A Laredo. | Received 2B Morgan Patterson from Double A Laredo. | Placed C Bill Miller on the 15-day disabled list. | Promoted 3B Chris Sanford to Double A Laredo. | Received RF Mike Wise from Double A Laredo. | Drafted CL Michael Huff in the 1961 first-year player draft (Round 6, Pick 5, 91st overall pick). | Drafted 1B Pablo Ramos in the 1961 first-year player draft (Round 7, Pick 5, 107th overall pick). | Drafted CL Roberto Peña in the 1961 first-year player draft (Round 8, Pick 5, 123rd overall pick). | Drafted 2B John McMuckin in the 1961 first-year player draft (Round 9, Pick 5, 139th overall pick). | Drafted SP Bill Tucker in the 1961 first-year player draft (Round 10, Pick 5, 155th overall pick). | Promoted RF Mike Wise to Double A Laredo. | Received 1B Cipriano Tobías from Double A Laredo. | Wednesday, May 24th, 1961 | Placed RF Curt MacGruder on the 15-day disabled list. | Monday, May 8th, 1961 | Activated RF Will Corbin from the disabled list. | Thursday, April 13th, 1961 | Placed RF Félix Román on the 15-day disabled list. | |
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