| Date | Player | No-Hitters | |
| 05/02/1951 | Brandon Owens | 9 K, 4 BB and 9 IP versus Edna while playing for Galveston | |
| 06/01/1952 | Jesús Vela | 5 K, 3 BB and 9 IP versus Harlingen while playing for Eagle Pass | |
| 05/27/1954 | Marvin Hartley | 3 K, 4 BB and 9 IP versus Eagle Pass while playing for Corpus Christi | |
| 05/28/1955 | Duane Bridges | 8 K, 0 BB and 9 IP versus Freeport while playing for Alice | |
| 06/10/1956 | Doug Stewart | 2 K, 1 BB and 9 IP versus Harlingen while playing for Corpus Christi | |
| 07/16/1956 | Joe Michaelis | 8 K, 4 BB and 9 IP versus Victoria while playing for San Antonio | |
| 04/27/1958 | Luis Méndez | 7 K, 2 BB and 9 IP versus San Antonio while playing for Kingsville | |
| 08/02/1959 | Todd Taylor | 6 K, 3 BB and 9 IP versus Alice while playing for Laredo | |
| 04/20/1960 | Tony Fernández | 3 K, 4 BB and 9 IP versus McAllen while playing for Freeport | |
| 07/04/1963 | Carlos Acosta | 6 K, 8 BB and 9 IP versus Tulsa while playing for Alice | |
| 06/01/1964 | Bill Yarbrough | 12 K, 1 BB and 9 IP versus Port Lavaca while playing for Austin | |
| 07/20/1965 | Héctor López | 5 K, 3 BB and 9 IP versus Victoria while playing for Edna | |
| 04/12/1966 | A.R. Page | 4 K, 2 BB and 9 IP versus Beeville while playing for Kingsville | |
| 05/10/1966 | Raúl Rodríguez | 2 K, 3 BB and 9 IP versus Edna while playing for Galveston | |
| 06/30/1966 | Eric Chambers | 6 K, 0 BB and 9 IP versus Beeville while playing for Galveston (PERFECT GAME) | |
| 07/28/1966 | Ron Gaston | 6 K, 0 BB and 9 IP versus McAllen while playing for Harlingen (PERFECT GAME) | |
| 06/09/1967 | Patrick Hodge | 10 K, 7 BB and 9 IP versus Eagle Pass while playing for Frankfort | |
| 05/24/1969 | Ben Shaffer | 5 K, 2 BB and 9 IP versus San Antonio while playing for Port Lavaca | |
| 06/14/1969 | Bill Marcotte | 8 K, 3 BB and 9 IP versus Corpus Christi while playing for Eagle Pass | |
| 07/18/1969 | Dave Rowe | 3 K, 3 BB and 9 IP versus Eagle Pass while playing for Harlingen | |
| 07/26/1969 | José Rivera | 9 K, 2 BB and 9 IP versus McAllen while playing for Harlingen | |
| 08/01/1970 | Enrique Méndez | 3 K, 0 BB and 9 IP versus Austin while playing for Kingsville | |
| 05/17/1971 | Rubén Rodríguez | 3 K, 3 BB and 9 IP versus Harlingen while playing for Corpus Christi | |
| 05/15/1972 | Javier Lima | 9 K, 1 BB and 9 IP versus Galveston while playing for Port Lavaca | |
| 05/30/1973 | Sam Dixon | 5 K, 1 BB and 9 IP versus Galveston while playing for Austin | |
| 04/13/1974 | Pedro Rodríguez | 0 K, 3 BB and 9 IP versus Port Lavaca while playing for Edna | |
| 07/03/1975 | Marcus Graves | 4 K, 2 BB and 9 IP versus Greensboro while playing for Kingsville | |
| 08/26/1977 | Jason Mason | 5 K, 5 BB and 9 IP versus Victoria while playing for Tulsa | |
| 04/22/1978 | Lee Fuller | 4 K, 5 BB and 9 IP versus Harlingen while playing for Brownsville | |
| 07/06/1978 | Dan Montgomery | 6 K, 0 BB and 9 IP versus Galveston while playing for Austin | |
| 04/26/1979 | José Franco | 5 K, 1 BB and 9 IP versus Corpus Christi while playing for McAllen | |
| 08/10/1979 | Xavier Velásquez | 4 K, 4 BB and 9 IP versus Laredo while playing for Eagle Pass | |
